Luigi Frigerio

( In Coll. Con G.Mangili, G.Aletti, F.Zanetto, E.Rabaiotti, E.Garavaglia )
Gynecol.Oncol. vol. 76, N.2, 249-250, 2000
Summary: Eleven patients with High Risk Endometrial Cancer have entered  the feasibility study at St.Raffaele Hospital-Milan University (mean age 58.8:range 48-67). After completion of Surgery the Pts. Received  P 60 mg/m2 via a continuous 1-h infusion once weekly during the 5 weeks of Radiotherapy (radiation dose 50.4 Gy). At the end of RT 3 additional consolidation courses of P 80 mg/m2 were performed.
Of the 11 enrolled patients, 10 have completed radiochemotherapy regimen. Concomitant P and RT is safe and accettable in pts with HREC. Prospective clinical studies are necessary to evaluate the benefits of this regimen for long term survival.